Jakob Kayne et son frère Samuel sont les derniers survivants du peuple des Hippocrates. Jakob est un combattant, mais aussi un Mange-Mémoire, capable de s'introduire n'importe où grâce à un don qui est aussi une malédiction : nul ne peut se souvenir de son visage. Samuel est l'héritier du savoir des plus grands guérisseurs. Ensemble, le guerrier et le médecin, ils sont devenus des mercenaires très prisés. Ils reçoivent la mission de guérir la fille malade d'un riche marchand. Mais celle-ci est coincée sur Isabela, une ville assiégée.
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